Chemicals and Drugs

Biguanides

Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Biguanide

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(65)

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AMA Style

References

  1. National Library of Medicine. Biguanides. Medical Subject Headings (MeSH). 2026. Unique ID D001645. http://id.nlm.nih.gov/mesh/2026/D001645
  2. Biguanides. In: Wikidata. https://www.wikidata.org/wiki/Q20064627