Chemicals and Drugs

Chlorhexidine

A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Chemical Identity

Chemical Information

Molecular Formula
C22H30Cl2N10
Molecular Weight
505.4 g/mol
CAS Registry No.
55-56-1
IUPAC Name
(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
InChIKey
GHXZTYHSJHQHIJ-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1N/C(=N/C(=NCCCCCCN=C(/N=C(/NC2=CC=C(C=C2)Cl)\N)N)N)/N)Cl
MeSH Unique ID
D002710
Source
PubChem CID 9552079

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Chlorhexidine Acetate
  • Chlorhexidine Hydrochloride
  • MK-412A
  • Novalsan
  • Sebidin A
  • Tubulicid
  • Acetate, Chlorhexidine
  • Hydrochloride, Chlorhexidine
  • MK 412A
  • MK412A

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

80(75); was see under BIGUANIDES 1975-79

MeSH Record

Previous Indexing

  • Biguanides (1968-1974)
  • Chlorobenzenes (1974)

MeSH Hierarchy

Tree Number

  1. D02w.078w.370.141.100w

MeSH Record

NLM Classification

QV 220

AMA Style

References

  1. National Library of Medicine. Chlorhexidine. Medical Subject Headings (MeSH). 2026. Unique ID D002710. http://id.nlm.nih.gov/mesh/2026/D002710
  2. Chlorhexidine. In: Wikipedia. https://en.wikipedia.org/wiki/Chlorhexidine
  3. Chlorhexidine. In: Wikidata. https://www.wikidata.org/wiki/Q15646788
  4. Chlorhexidine. In: PubChem Compound. CID 9552079. https://pubchem.ncbi.nlm.nih.gov/compound/9552079