Chemicals and Drugs

Biperiden

A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.

Chemical Identity

Chemical Information

Molecular Formula
C21H29NO
Molecular Weight
311.5 g/mol
CAS Registry No.
514-65-8
IUPAC Name
1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol
InChIKey
YSXKPIUOCJLQIE-UHFFFAOYSA-N
SMILES
C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O
MeSH Unique ID
D001712
Source
PubChem CID 2381

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Biperidene
  • alpha-Bicyclo(2.2.1)hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol
  • Akineton
  • Biperiden Hydrochloride
  • Biperiden, 1R-(1 alpha,2 alpha(R*),4 alpha)-Isomer
  • Biperiden, 1S-(1 alpha,2 alpha(R*),4 alpha)-Isomer
  • Hydrochloride, Biperiden

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(66); was see under PIPERIDINES 1966-90

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.100.080.100w
  2. D03w.383.621.110w
  3. D03w.605.084.500.332w

AMA Style

References

  1. National Library of Medicine. Biperiden. Medical Subject Headings (MeSH). 2026. Unique ID D001712. http://id.nlm.nih.gov/mesh/2026/D001712
  2. Biperiden. In: Wikipedia. https://en.wikipedia.org/wiki/Biperiden
  3. Biperiden. In: Wikidata. https://www.wikidata.org/wiki/Q414914
  4. Biperiden. In: PubChem Compound. CID 2381. https://pubchem.ncbi.nlm.nih.gov/compound/2381