Structured Summary
Abstract
Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
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Classification
Broader headings
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Synonyms
11 entry terms
- Cdk1 Protein Kinase
- Cyclin-Dependent Kinase 1
- cdc2+ Protein
- cdk1 Kinase
- Cyclin Dependent Kinase 1
- Protein Kinase, CDC2
- Protein Kinase, Cdk1
- Histone Kinase p34(cdc2)
- Protein p34cdc2
- p34cdc2 Protein
- p34cdc2, Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2004(1991)
MeSH Record
Previous Indexing
- Phosphoproteins (1987-1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. CDC2 Protein Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D016203. http://id.nlm.nih.gov/mesh/2026/D016203
- CDC2 Protein Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Cyclin-dependent_kinase_1
- CDC2 Protein Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q1147372