Chemicals and Drugs

Carubicin

A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.

Chemical Identity

Chemical Information

Molecular Formula
C26H27NO10
Molecular Weight
513.5 g/mol
CAS Registry No.
50935-04-1
IUPAC Name
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione
InChIKey
XREUEWVEMYWFFA-CSKJXFQVSA-N
SMILES
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)O)O)(C(=O)C)O)N)O
MeSH Unique ID
D002360
Source
PubChem CID 443831

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • Carminomicin
  • Carminomycin
  • Carminomycin I
  • Demethyldaunomycin
  • Demethyldaunorubicin
  • Karminomicin
  • Karminomycin
  • Carminomycin II
  • Carminomycin III
  • Carubicin Hydrochloride
  • NSC-180,024
  • NSC-180024
  • Rubeomycin A
  • Rubeomycin A1
  • Hydrochloride, Carubicin
  • NSC 180,024
  • NSC 180024
  • NSC180,024
  • NSC180024

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(84); was see under DAUNORUBICIN/analogs & derivatives 1984-90; was CARMINOMYCIN see under DAUNORUBICIN 1980-83 & see under ANTIBIOTICS, ANTINEOPLASTIC 1975-79

MeSH Record

Previous Indexing

  • Aminoglycosides (1974)
  • Antibiotics, Antineoplastic (1967-1974)
  • Naphthacenes (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.562.050.200w.150w
  2. D04w.615w.562.050.200w.150w
  3. D09w.408w.051.059.200w.150w

AMA Style

References

  1. National Library of Medicine. Carubicin. Medical Subject Headings (MeSH). 2026. Unique ID D002360. http://id.nlm.nih.gov/mesh/2026/D002360
  2. Carubicin. In: Wikipedia. https://en.wikipedia.org/wiki/Carubicin
  3. Carubicin. In: Wikidata. https://www.wikidata.org/wiki/Q5047474
  4. Carubicin. In: PubChem Compound. CID 443831. https://pubchem.ncbi.nlm.nih.gov/compound/443831