Structured Summary
Abstract
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
Chemical Identity
Chemical Information
- Molecular Formula
- C27H29NO10
- Molecular Weight
- 527.5 g/mol
- CAS Registry No.
- 20830-81-3
- IUPAC Name
- (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
- InChIKey
- STQGQHZAVUOBTE-VGBVRHCVSA-N
- SMILES
- C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O
- MeSH Unique ID
- D003630
- Source
- PubChem CID 30323
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
13 entry terms
- Dauno-Rubidomycine
- Daunomycin
- Rubidomycin
- Rubomycin
- Dauno Rubidomycine
- Cerubidine
- Daunoblastin
- Daunoblastine
- Daunorubicin Hydrochloride
- NSC-82151
- Hydrochloride, Daunorubicin
- NSC 82151
- NSC82151
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
80; was DAUNOMYCIN 1964-79 (Prov 1964-65)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Daunorubicin. Medical Subject Headings (MeSH). 2026. Unique ID D003630. http://id.nlm.nih.gov/mesh/2026/D003630
- Daunorubicin. In: Wikipedia. https://en.wikipedia.org/wiki/Daunorubicin
- Daunorubicin. In: Wikidata. https://www.wikidata.org/wiki/Q411659
- Daunorubicin. In: PubChem Compound. CID 30323. https://pubchem.ncbi.nlm.nih.gov/compound/30323