Chemicals and Drugs

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against BREAST NEOPLASMS; LYMPHOMA; and LEUKEMIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An orally administered anthracycline antineoplastic. The compound has shown activity against BREAST NEOPLASMS; LYMPHOMA; and LEUKEMIA.

Chemical Identity

Chemical Information

Molecular Formula
C26H27NO9
Molecular Weight
497.5 g/mol
CAS Registry No.
58957-92-9
IUPAC Name
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
InChIKey
XDXDZDZNSLXDNA-TZNDIEGXSA-N
SMILES
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O
MeSH Unique ID
D015255
Source
PubChem CID 42890

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • 4-Demethoxydaunorubicin
  • 4-Desmethoxydaunorubicin
  • 4 Demethoxydaunorubicin
  • 4 Desmethoxydaunorubicin
  • IMI-30
  • Idarubicin Hydrochloride
  • NSC-256439
  • Hydrochloride, Idarubicin
  • IMI 30
  • IMI30
  • NSC 256439
  • NSC256439

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Antibiotics, Antineoplastic (1967-1988)
  • Daunorubicin/analogs & derivatives (1975-1988)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.562.050.200w.300w
  2. D04w.615w.562.050.200w.300w
  3. D09w.408w.051.059.200w.300w

AMA Style

References

  1. National Library of Medicine. Idarubicin. Medical Subject Headings (MeSH). 2026. Unique ID D015255. http://id.nlm.nih.gov/mesh/2026/D015255
  2. Idarubicin. In: Wikipedia. https://en.wikipedia.org/wiki/Idarubicin
  3. Idarubicin. In: Wikidata. https://www.wikidata.org/wiki/Q1063862
  4. Idarubicin. In: PubChem Compound. CID 42890. https://pubchem.ncbi.nlm.nih.gov/compound/42890