Chemicals and Drugs

Doxorubicin

Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.

Chemical Identity

Chemical Information

Molecular Formula
C27H29NO11
Molecular Weight
543.5 g/mol
CAS Registry No.
23214-92-8
IUPAC Name
(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
InChIKey
AOJJSUZBOXZQNB-TZSSRYMLSA-N
SMILES
C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O
MeSH Unique ID
D004317
Source
PubChem CID 31703

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

26 entry terms
  • Adriablastin
  • Adriablastine
  • Adriamycin
  • Adriblastin
  • Adriblastina
  • Adriblastine
  • Adrimedac
  • DOXO-cell
  • Doxolem
  • Doxorubicin Hexal
  • Doxorubicin Hydrochloride
  • Doxorubicin NC
  • Doxorubicina Ferrer Farm
  • Doxorubicina Funk
  • Doxorubicina Tedec
  • Doxorubicine Baxter
  • Doxotec
  • Farmiblastina
  • Myocet
  • Onkodox
  • Ribodoxo
  • Rubex
  • Urokit Doxo-cell
  • DOXO cell
  • Hydrochloride, Doxorubicin
  • Urokit Doxo cell

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

78(73)

MeSH Record

Previous Indexing

  • Antibiotics, Antineoplastic (1967-1972)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.426w.559w.847w.562.050.200w.175w
  2. D04w.615w.562.050.200w.175w
  3. D09w.408w.051.059.200w.175w

MeSH Record

NLM Classification

QV 269

AMA Style

References

  1. National Library of Medicine. Doxorubicin. Medical Subject Headings (MeSH). 2026. Unique ID D004317. http://id.nlm.nih.gov/mesh/2026/D004317
  2. Doxorubicin. In: Wikipedia. https://en.wikipedia.org/wiki/Doxorubicin
  3. Doxorubicin. In: Wikidata. https://www.wikidata.org/wiki/Q18936
  4. Doxorubicin. In: PubChem Compound. CID 31703. https://pubchem.ncbi.nlm.nih.gov/compound/31703