Chemicals and Drugs

Caspase 10

A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

12 entry terms
  • Caspase-10
  • Caspase 10-a
  • Caspase 10-c
  • Caspase 10-d
  • Caspase 10a
  • Caspase 10c
  • Caspase 10d
  • Mch4 Protease
  • Caspase 10 a
  • Caspase 10 c
  • Caspase 10 d
  • Protease, Mch4

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1998)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.262w.500.126w.550.910
  2. D08.811w.277w.656w.300w.200.126w.550.910
  3. D12.776w.476.075.405w.550.910

AMA Style

References

  1. National Library of Medicine. Caspase 10. Medical Subject Headings (MeSH). 2026. Unique ID D053455. http://id.nlm.nih.gov/mesh/2026/D053455
  2. Caspase 10. In: Wikidata. https://www.wikidata.org/wiki/Q32855883