Chemicals and Drugs

Cefmenoxime

A cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

Chemical Identity

Chemical Information

Molecular Formula
C16H17N9O5S3
Molecular Weight
511.6 g/mol
CAS Registry No.
65085-01-0
IUPAC Name
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
HJJDBAOLQAWBMH-YCRCPZNHSA-N
SMILES
CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)O
MeSH Unique ID
D015281
Source
PubChem CID 9570757

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Abbott-50192
  • Cefmax
  • Cefmenoxime Hydrochloride
  • Cefmenoxime Hydrochloride (2:1)
  • SCE-1365
  • Abbott 50192
  • Abbott50192
  • Hydrochloride, Cefmenoxime
  • SCE 1365
  • SCE1365

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Cefotaxime (1982-1988)
  • Cephalosporins (1979-1981)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.190w.190w.125w
  2. D02w.886w.665w.074w.190w.190w.125w
  3. D03w.633.100.300w.249w.190w.190w.125w

AMA Style

References

  1. National Library of Medicine. Cefmenoxime. Medical Subject Headings (MeSH). 2026. Unique ID D015281. http://id.nlm.nih.gov/mesh/2026/D015281
  2. Cefmenoxime. In: Wikipedia. https://en.wikipedia.org/wiki/Cefmenoxime
  3. Cefmenoxime. In: Wikidata. https://www.wikidata.org/wiki/Q4921166
  4. Cefmenoxime. In: PubChem Compound. CID 9570757. https://pubchem.ncbi.nlm.nih.gov/compound/9570757