Chemicals and Drugs

Cefotaxime

Semisynthetic broad-spectrum cephalosporin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Semisynthetic broad-spectrum cephalosporin.

Chemical Identity

Chemical Information

Molecular Formula
C16H17N5O7S2
Molecular Weight
455.5 g/mol
CAS Registry No.
63527-52-6
IUPAC Name
(6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey
GPRBEKHLDVQUJE-QSWIMTSFSA-N
SMILES
CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)O
MeSH Unique ID
D002439
Source
PubChem CID 5742673

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • Cefotaxim
  • Cephotaxim
  • Benaxima
  • Biosint
  • Cefotaxime Sodium
  • Cefradil
  • Claforan
  • Fotexina
  • HR-756
  • Kendrick
  • Klaforan
  • Primafen
  • Ru-24756
  • Taporin
  • HR 756
  • HR756
  • Ru 24756
  • Ru24756
  • Sodium, Cefotaxime

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

82

MeSH Record

Previous Indexing

  • Cephalosporins (1966-1981)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.249w.190w.190w
  2. D02w.886w.665w.074w.190w.190w
  3. D03w.633.100.300w.249w.190w.190w

MeSH Record

NLM Classification

QV 350.5.C3

AMA Style

References

  1. National Library of Medicine. Cefotaxime. Medical Subject Headings (MeSH). 2026. Unique ID D002439. http://id.nlm.nih.gov/mesh/2026/D002439
  2. Cefotaxime. In: Wikipedia. https://en.wikipedia.org/wiki/Cefotaxime
  3. Cefotaxime. In: Wikidata. https://www.wikidata.org/wiki/Q417968
  4. Cefotaxime. In: PubChem Compound. CID 5742673. https://pubchem.ncbi.nlm.nih.gov/compound/5742673