Chemicals and Drugs

Chimerin 1

A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.

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Classification

Broader headings

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MeSH Record

Synonyms

24 entry terms
  • Chimaerin 1
  • alpha-1 Chimaerin
  • alpha-1 Chimerin
  • alpha-Chimaerin
  • alpha-Chimerin
  • alpha1-Chimaerin
  • arhGAP2 Protein
  • n-Chimaerin
  • n-Chimerin
  • rhoGAP2 Protein
  • Chimaerin, alpha-1
  • Chimerin, alpha-1
  • alpha 1 Chimaerin
  • alpha 1 Chimerin
  • alpha Chimaerin
  • alpha Chimerin
  • alpha1 Chimaerin
  • n Chimaerin
  • alpha-2 Chimaerin
  • alpha-2 Chimerin
  • Chimaerin, alpha-2
  • Chimerin, alpha-2
  • alpha 2 Chimaerin
  • alpha 2 Chimerin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000; use CHIMERIN 1 (NM) 1990-1999; for ALPHA1-CHIMAERIN use GTPASE-ACTIVATING PROTEINS (NM) 1996-1999

MeSH Record

Previous Indexing

  • Nerve Tissue Proteins (1991-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Chimerin 1. Medical Subject Headings (MeSH). 2026. Unique ID D020848. http://id.nlm.nih.gov/mesh/2026/D020848
  2. Chimerin 1. In: Wikidata. https://www.wikidata.org/wiki/Q21100737