Chemicals and Drugs

GTP-Binding Protein Regulators

Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three categories depending upon whether they stimulate GTPase activity (GTPASE-ACTIVATING PROTEINS), inhibit release of GDP; (GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Proteins that regulate the signaling activity of GTP-BINDING PROTEINS. They are divided into three categories depending upon whether they stimulate GTPase activity (GTPASE-ACTIVATING PROTEINS), inhibit release of GDP; (GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS); or exchange GTP for GDP; (GUANINE NUCLEOTIDE EXCHANGE FACTORS).

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

Synonyms

12 entry terms
  • G-Protein Regulating Factors
  • G-Protein Signaling Regulators
  • Regulating Factors, G-Protein
  • Regulating Factors, GTP-Binding Protein
  • Regulators, G-Protein Signaling
  • G Protein Regulating Factors
  • G Protein Signaling Regulators
  • GTP Binding Protein Regulators
  • Regulating Factors, GTP Binding Protein
  • Regulators, G Protein Signaling
  • Regulators, GTP-Binding Protein
  • Signaling Regulators, G-Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with RGS PROTEINS

MeSH Record

History Note

2000

MeSH Record

Previous Indexing

  • G-Proteins (1988-1999)
  • Proteins (1978-1999)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.325w
  2. D12.776w.476.325w

MeSH Record

NLM Classification

QU 55.2

AMA Style

References

  1. National Library of Medicine. GTP-Binding Protein Regulators. Medical Subject Headings (MeSH). 2026. Unique ID D020555. http://id.nlm.nih.gov/mesh/2026/D020555
  2. GTP-Binding Protein Regulators. In: Wikipedia. https://en.wikipedia.org/wiki/GTP-binding_protein_regulators
  3. GTP-Binding Protein Regulators. In: Wikidata. https://www.wikidata.org/wiki/Q5514732