Chemicals and Drugs

Guanine Nucleotide Exchange Factors

Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protein factors that promote the exchange of GTP for GDP bound to GTP-BINDING PROTEINS.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

15 entry terms
  • GDP Dissociation Factor
  • GDP Dissociation Stimulators
  • GDP Exchange Factors
  • GDP-GTP Exchange Protein
  • GDP-GTP Reversing Factors
  • Guanine Nucleotide Exchange Factor
  • Guanine Nucleotide Releasing Factors
  • Guanine-Nucleotide-Releasing Factor
  • Exchange Factors, GDP
  • Factors, GDP Exchange
  • Factors, GDP-GTP Reversing
  • GDP GTP Exchange Protein
  • GDP GTP Reversing Factors
  • Guanine Nucleotide Releasing Factor
  • Reversing Factors, GDP-GTP

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2000; use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1978-1999; for GDP-GTP EXCHANGE PROTEIN use RAB3 GTP-BINDING PROTEINS (NM) 1994-1999; for GDP DISSOCIATION FACTOR use RAP GTP-BINDING PROTEINS (NM) 1996-1999

MeSH Record

Previous Indexing

  • G-Proteins (1994-1999)
  • Proteins (1978-1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Guanine Nucleotide Exchange Factors. Medical Subject Headings (MeSH). 2026. Unique ID D020662. http://id.nlm.nih.gov/mesh/2026/D020662
  2. Guanine Nucleotide Exchange Factors. In: Wikipedia. https://en.wikipedia.org/wiki/Guanine_nucleotide_exchange_factor
  3. Guanine Nucleotide Exchange Factors. In: Wikidata. https://www.wikidata.org/wiki/Q901088