Structured Summary
Abstract
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
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Synonyms
19 entry terms
- ARHGEF1
- Cool-1 Protein
- PAK-Interacting Exchange Factor beta
- Rho Guanine Nucleotide Exchange Factor (GEF) 1
- Rho Guanine Nucleotide Exchange Factor 6
- Rho Guanine Nucleotide Exchange Factor 7
- Rho Guanine Nucleotide Exchange Factor p115
- RhoGEF
- beta PIX Protein
- betaPIX Protein
- p115 RhoGEF
- p115RhoGEF
- Cool 1 Protein
- PAK Interacting Exchange Factor beta
- PIX Protein, beta
- Protein, Cool-1
- Protein, beta PIX
- Protein, betaPIX
- RhoGEF, p115
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
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AMA Style
References
- National Library of Medicine. Rho Guanine Nucleotide Exchange Factors. Medical Subject Headings (MeSH). 2026. Unique ID D064067. http://id.nlm.nih.gov/mesh/2026/D064067
- Rho Guanine Nucleotide Exchange Factors. In: Wikidata. https://www.wikidata.org/wiki/Q78190114