Chemicals and Drugs

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

Chemical Identity

Chemical Information

Molecular Formula
C7H4ClNO2
Molecular Weight
169.56 g/mol
CAS Registry No.
95-25-0
IUPAC Name
5-chloro-3H-1,3-benzoxazol-2-one
InChIKey
TZFWDZFKRBELIQ-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1Cl)NC(=O)O2
MeSH Unique ID
D002753
Source
PubChem CID 2733

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Paraflex
  • Parafon
  • Parafon Forte DSC

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(66); was see under BENZOXAZOLES 1966-90

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Chlorzoxazone. Medical Subject Headings (MeSH). 2026. Unique ID D002753. http://id.nlm.nih.gov/mesh/2026/D002753
  2. Chlorzoxazone. In: Wikipedia. https://en.wikipedia.org/wiki/Chlorzoxazone
  3. Chlorzoxazone. In: Wikidata. https://www.wikidata.org/wiki/Q3294630
  4. Chlorzoxazone. In: PubChem Compound. CID 2733. https://pubchem.ncbi.nlm.nih.gov/compound/2733