Structured Summary
Abstract
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
8 entry terms
- Brain-Specific 24S-Hydroxylase
- Brain Specific 24S Hydroxylase
- Cholesterol 24 Hydroxylase
- 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
- CYP46A1
- Cholestane Tetrol 24-Hydroxylase
- Cytochrome P450 46A1
- Cholestane Tetrol 24 Hydroxylase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1999)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Cholesterol 24-Hydroxylase. Medical Subject Headings (MeSH). 2026. Unique ID D000072556. http://id.nlm.nih.gov/mesh/2026/D000072556
- Cholesterol 24-Hydroxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Cholesterol_24-hydroxylase
- Cholesterol 24-Hydroxylase. In: Wikidata. https://www.wikidata.org/wiki/Q59251948