Chemicals and Drugs

Chromatin Assembly Factor-1

A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.

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Classification

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MeSH Record

Synonyms

9 entry terms
  • Chromatin Assembly Complex-1
  • Assembly Complex-1, Chromatin
  • Assembly Factor-1, Chromatin
  • Chromatin Assembly Complex 1
  • Chromatin Assembly Factor 1
  • Chromatin Assembly Complex-1, p150 Subunit
  • Chromatin Assembly Complex-1, p60 Subunit
  • Chromatin Assembly Complex 1, p150 Subunit
  • Chromatin Assembly Complex 1, p60 Subunit

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010(1995)

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AMA Style

References

  1. National Library of Medicine. Chromatin Assembly Factor-1. Medical Subject Headings (MeSH). 2026. Unique ID D056504. http://id.nlm.nih.gov/mesh/2026/D056504
  2. Chromatin Assembly Factor-1. In: Wikipedia. https://en.wikipedia.org/wiki/Chromatin_assembly_factor_1
  3. Chromatin Assembly Factor-1. In: Wikidata. https://www.wikidata.org/wiki/Q21746404