Chemicals and Drugs

Retinoblastoma-Binding Protein 4

A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and repression of GENETIC TRANSCRIPTION. Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 and polycomb repressive complex 2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and repression of GENETIC TRANSCRIPTION. Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 and polycomb repressive complex 2.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

11 entry terms
  • Chromatin Assembly Factor 1 Subunit C
  • Nucleosome-Remodeling Factor Subunit RBAP48
  • RBBP4 Protein
  • RbAp48 Protein
  • Retinoblastoma p48-Binding Protein
  • p48 Subunit, Chromatin Assembly Factor-1
  • Nucleosome Remodeling Factor Subunit RBAP48
  • Retinoblastoma Binding Protein 4
  • Retinoblastoma p48 Binding Protein
  • p48 Subunit, Chromatin Assembly Factor 1
  • p48-Binding Protein, Retinoblastoma

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010

MeSH Hierarchy

Tree Numbers

  1. D05.500w.781w.750w.500
  2. D08.811w.277w.087w.520w.500w.775
  3. D08.811w.277w.087w.520w.750.775
  4. D08.811w.600w.620w.775
  5. D08.811w.600w.795.775
  6. D12.644w.360.024w.328.600
  7. D12.776w.157w.057w.158.600
  8. D12.776w.476.024w.420.600
  9. D12.776w.580w.219.200w.500
  10. D12.776w.660w.235.600w.200w.500
  11. D12.776w.660w.769.600
  12. D12.776w.664w.235.800w.200w.500
  13. D12.776w.930w.780.890w.200w.500

AMA Style

References

  1. National Library of Medicine. Retinoblastoma-Binding Protein 4. Medical Subject Headings (MeSH). 2026. Unique ID D056505. http://id.nlm.nih.gov/mesh/2026/D056505
  2. Retinoblastoma-Binding Protein 4. In: Wikidata. https://www.wikidata.org/wiki/Q21105772