Chemicals and Drugs

Chromomycin A3

Glycosidic antibiotic from Streptomyces griseus used as a fluorescent stain of DNA and as an antineoplastic agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Glycosidic antibiotic from Streptomyces griseus used as a fluorescent stain of DNA and as an antineoplastic agent.

Chemical Identity

Chemical Information

Molecular Formula
C57H82O26
Molecular Weight
1183.2 g/mol
CAS Registry No.
74913-06-7
IUPAC Name
[6-[[(6S,7S)-6-[4-[4-(5-acetyloxy-4-hydroxy-4,6-dimethyloxan-2-yl)oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-7-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-4,10-dihydroxy-3-methyl-5-oxo-7,8-dihydro-6H-anthracen-2-yl]oxy]-4-(4-hydroxy-5-methoxy-6-methyloxan-2-yl)oxy-2-methyloxan-3-yl] acetate
InChIKey
ZYVSOIYQKUDENJ-MNGCYDFMSA-N
SMILES
CC1C(C(CC(O1)O[C@H]2[C@@H](CC3=C(C2=O)C(=C4C(=C3)C=C(C(=C4O)C)OC5CC(C(C(O5)C)OC(=O)C)OC6CC(C(C(O6)C)OC)O)O)[C@@H](C(=O)[C@H]([C@@H](C)O)O)OC)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)OC(=O)C)(C)O)O
MeSH Unique ID
D014128
Source
PubChem CID 5351560

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Toyomicin
  • Toyomycin

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was TOYOMICIN see under CHROMOMYCINS 1975-90

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Chromomycin A3. Medical Subject Headings (MeSH). 2026. Unique ID D014128. http://id.nlm.nih.gov/mesh/2026/D014128
  2. Chromomycin A3. In: Wikidata. https://www.wikidata.org/wiki/Q77569519
  3. Chromomycin A3. In: PubChem Compound. CID 5351560. https://pubchem.ncbi.nlm.nih.gov/compound/5351560