Structured Summary
Abstract
A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.
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Classification
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
1 entry terms
- Chromomycin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
antineoplastic antibiotics
MeSH Record
History Note
73(72)
MeSH Record
Previous Indexing
- Antibiotics, Antineoplastic (1967-1971)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Chromomycins. Medical Subject Headings (MeSH). 2026. Unique ID D002865. http://id.nlm.nih.gov/mesh/2026/D002865
- Chromomycins. In: Wikidata. https://www.wikidata.org/wiki/Q99050645