Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Chromosome Painting

A technique for visualizing CHROMOSOME ABERRATIONS using fluorescently labeled DNA probes which are hybridized to chromosomal DNA. Multiple fluorochromes may be attached to the probes. Upon hybridization, this produces a multicolored, or painted, effect with a unique color at each site of hybridization. This technique may also be used to identify cross-species homology by labeling probes from one species for hybridization with chromosomes from another species.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A technique for visualizing CHROMOSOME ABERRATIONS using fluorescently labeled DNA probes which are hybridized to chromosomal DNA. Multiple fluorochromes may be attached to the probes. Upon hybridization, this produces a multicolored, or painted, effect with a unique color at each site of hybridization. This technique may also be used to identify cross-species homology by labeling probes from one species for hybridization with chromosomes from another species.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

3 entry terms
  • Chromosome Paintings
  • Painting, Chromosome
  • Paintings, Chromosome

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

History Note

1999

MeSH Record

Previous Indexing

  • In Situ Hybridization, Fluorescence (1993-1998)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.500.620.670w.325w.350w.125
  2. E01w.370.225.750.600.670w.325w.350w.125
  3. E05.200.500.620.670w.325w.350w.125
  4. E05.200.750.600.670w.325w.350w.125
  5. E05.393.285.350w.125
  6. E05.393.661w.475w.350w.125

AMA Style

References

  1. National Library of Medicine. Chromosome Painting. Medical Subject Headings (MeSH). 2026. Unique ID D020223. http://id.nlm.nih.gov/mesh/2026/D020223
  2. Chromosome Painting. In: Wikidata. https://www.wikidata.org/wiki/Q72088750