Chemicals and Drugs

Cinnarizine

A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.

Chemical Identity

Chemical Information

Molecular Formula
C26H28N2
Molecular Weight
368.5 g/mol
CAS Registry No.
298-57-7
IUPAC Name
1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine
InChIKey
DERZBLKQOCDDDZ-JLHYYAGUSA-N
SMILES
C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4
MeSH Unique ID
D002936
Source
PubChem CID 1547484

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

27 entry terms
  • 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine
  • Cinarizine
  • Cinarizina Inkey
  • Cinarizina Ratiopharm
  • Cinazière
  • Cinna
  • Cinnarizin AL
  • Cinnarizin Siegfried
  • Cinnarizin Von Ct
  • Cinnarizin-Ratiopharm
  • Cinnarizine L-Tartrate
  • Cinnarizine L-Tartrate (1:1)
  • Cinnarizine, (E)-Isomer
  • Cinnarizine, Dihydrochloride
  • Cinnipirine
  • Cisaken
  • Dimitronal
  • R-516
  • Stugeron
  • Stugeron Forte
  • Cinnarizin Ratiopharm
  • Cinnarizine L Tartrate
  • Dihydrochloride Cinnarizine
  • L-Tartrate, Cinnarizine
  • R 516
  • R516
  • Von Ct, Cinnarizin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86(75)

MeSH Record

Previous Indexing

  • Cinnamates (1971-1974)
  • Piperazines (1968-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.606w.290w

AMA Style

References

  1. National Library of Medicine. Cinnarizine. Medical Subject Headings (MeSH). 2026. Unique ID D002936. http://id.nlm.nih.gov/mesh/2026/D002936
  2. Cinnarizine. In: Wikipedia. https://en.wikipedia.org/wiki/Cinnarizine
  3. Cinnarizine. In: Wikidata. https://www.wikidata.org/wiki/Q775073
  4. Cinnarizine. In: PubChem Compound. CID 1547484. https://pubchem.ncbi.nlm.nih.gov/compound/1547484