Chemicals and Drugs

Citalopram

A furancarbonitrile that is one of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A furancarbonitrile that is one of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.

Chemical Identity

Chemical Information

Molecular Formula
C20H21FN2O
Molecular Weight
324.4 g/mol
CAS Registry No.
59729-33-8
IUPAC Name
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
InChIKey
WSEQXVZVJXJVFP-UHFFFAOYSA-N
SMILES
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
MeSH Unique ID
D015283
Source
PubChem CID 2771

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Cytalopram
  • Celexa
  • Citalopram Hydrobromide
  • Lu-10-171
  • Seropram
  • Lu10171

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1989; for ESCITALOPRAM use CITALOPRAM (NM) 2001-2002

MeSH Record

Previous Indexing

  • Antidepressive Agents (1977-1988)
  • Propylamines (1977-1988)
  • Serotonin Antagonists (1978-1988)

MeSH Hierarchy

Tree Numbers

  1. D02w.092w.831.170w
  2. D02w.626w.320w
  3. D03w.633.100.127w.187w

AMA Style

References

  1. National Library of Medicine. Citalopram. Medical Subject Headings (MeSH). 2026. Unique ID D015283. http://id.nlm.nih.gov/mesh/2026/D015283
  2. Citalopram. In: Wikipedia. https://en.wikipedia.org/wiki/Citalopram
  3. Citalopram. In: Wikidata. https://www.wikidata.org/wiki/Q409672
  4. Citalopram. In: PubChem Compound. CID 2771. https://pubchem.ncbi.nlm.nih.gov/compound/2771