Structured Summary
Abstract
A serine protease that cleaves multiple COMPLEMENT 3 into COMPLEMENT 3A (anaphylatoxin) and COMPLEMENT 3B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of COMPLEMENT 4B and COMPLEMENT 2A (C4b2a).
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
5 entry terms
- C3 Convertase (C4b2a)
- Classical C3 Convertase
- Classical Pathway C3 Convertase
- Complement C3 Convertase, Classical Pathway
- C3 Convertase, Classical
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006
MeSH Record
Previous Indexing
- Complement C3-C5 Convertases (1979-2005)
- Complement Pathway, Classical (1980-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Classical Pathway Complement C3 Convertase. Medical Subject Headings (MeSH). 2026. Unique ID D051574. http://id.nlm.nih.gov/mesh/2026/D051574
- Classical Pathway Complement C3 Convertase. In: Wikidata. https://www.wikidata.org/wiki/Q78325571