Chemicals and Drugs

Clomiphene

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.

Chemical Identity

Chemical Information

Molecular Formula
C26H28ClNO
Molecular Weight
406.0 g/mol
CAS Registry No.
911-45-5
IUPAC Name
2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine
InChIKey
GKIRPKYJQBWNGO-UHFFFAOYSA-N
SMILES
CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
MeSH Unique ID
D002996
Source
PubChem CID 2800

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Chloramiphene
  • Clomifen
  • Clomifene
  • Clomid
  • Clomide
  • Clomiphene Citrate
  • Clomiphene Hydrochloride
  • Clostilbegit
  • Dyneric
  • Gravosan
  • Klostilbegit
  • Serophene
  • Citrate, Clomiphene
  • Hydrochloride, Clomiphene

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

68(64); CLOMIFENE was CLOMIFEN 1978-91

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Clomiphene. Medical Subject Headings (MeSH). 2026. Unique ID D002996. http://id.nlm.nih.gov/mesh/2026/D002996
  2. Clomiphene. In: Wikipedia. https://en.wikipedia.org/wiki/Clomifene
  3. Clomiphene. In: Wikidata. https://www.wikidata.org/wiki/Q418730
  4. Clomiphene. In: PubChem Compound. CID 2800. https://pubchem.ncbi.nlm.nih.gov/compound/2800