Phenomena and Processes

Clonal Deletion

Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.

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Classification

Broader headings

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See Also

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Synonyms

7 entry terms
  • Clonal Deletions
  • Deletion, Clonal
  • Deletions, Clonal
  • Clonal Abortion
  • Abortion, Clonal
  • Abortions, Clonal
  • Clonal Abortions

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

a form of immune tolerance

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History Note

94

MeSH Record

Previous Indexing

  • Clone Cells (1978-1993)
  • Immune Tolerance (1978-1993)
  • specific cell/immunology (1978-1993)

MeSH Hierarchy

Tree Number

  1. G12.535w.425w.120w

AMA Style

References

  1. National Library of Medicine. Clonal Deletion. Medical Subject Headings (MeSH). 2026. Unique ID D017637. http://id.nlm.nih.gov/mesh/2026/D017637
  2. Clonal Deletion. In: Wikipedia. https://en.wikipedia.org/wiki/Clonal_deletion
  3. Clonal Deletion. In: Wikidata. https://www.wikidata.org/wiki/Q5134952