Phenomena and Processes

Self Tolerance

The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system.

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Classification

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Synonyms

3 entry terms
  • Self Tolerances
  • Tolerance, Self
  • Tolerances, Self

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

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Indexing Annotation

a form of immune tolerance

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History Note

94

MeSH Record

Previous Indexing

  • Immune Tolerance (1973-1993)

MeSH Hierarchy

Tree Number

  1. G12.535w.425w.800

AMA Style

References

  1. National Library of Medicine. Self Tolerance. Medical Subject Headings (MeSH). 2026. Unique ID D017634. http://id.nlm.nih.gov/mesh/2026/D017634
  2. Self Tolerance. In: Wikidata. https://www.wikidata.org/wiki/Q71131273