Chemicals and Drugs

Clopenthixol

A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

Chemical Identity

Chemical Information

Molecular Formula
C22H25ClN2OS
Molecular Weight
401.0 g/mol
CAS Registry No.
982-24-1
IUPAC Name
2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol
InChIKey
WFPIAZLQTJBIFN-UHFFFAOYSA-N
SMILES
C1CN(CCN1CCC=C2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
MeSH Unique ID
D003006
Source
PubChem CID 12454

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Cisordinol
  • Zuclopenthixol
  • alpha-Clopenthixol
  • alpha Clopenthixol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(63); was see under THIOXANTHENES 1975-90; was see under TRANQUILIZING AGENTS 1967-74

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Clopenthixol. Medical Subject Headings (MeSH). 2026. Unique ID D003006. http://id.nlm.nih.gov/mesh/2026/D003006
  2. Clopenthixol. In: Wikipedia. https://en.wikipedia.org/wiki/Clopenthixol
  3. Clopenthixol. In: Wikidata. https://www.wikidata.org/wiki/Q413000
  4. Clopenthixol. In: PubChem Compound. CID 12454. https://pubchem.ncbi.nlm.nih.gov/compound/12454