Structured Summary
Abstract
The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- C5b Complement
- Complement 5b
- Complement Component 5b
- C5b, Complement
- Complement, C5b
- Component 5b, Complement
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1982)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Complement C5b. Medical Subject Headings (MeSH). 2026. Unique ID D050776. http://id.nlm.nih.gov/mesh/2026/D050776
- Complement C5b. In: Wikidata. https://www.wikidata.org/wiki/Q76851178