Structured Summary
Abstract
A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
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Classification
Broader headings
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Synonyms
13 entry terms
- AML3 Transcription Factor
- Acute Myeloid Leukemia 3 Protein
- CBFA-1 Protein
- CBFA1 Protein
- CBFalpha Runt Domain Transcription Factor 1
- CBFalpha1 Protein
- Osf2 Transcription Factor
- PEBP2alphaA Protein
- Runx2 Protein
- SEF1 Protein
- SL3-3 Enhancer Factor 1
- CBFA 1 Protein
- SL3 3 Enhancer Factor 1
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
see SCR for organism-specific terms
MeSH Record
History Note
2006(1997)
MeSH Record
Previous Indexing
- Neoplasm Proteins (1997-2005)
- Transcription Factors (1997-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Core Binding Factor Alpha 1 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D050659. http://id.nlm.nih.gov/mesh/2026/D050659
- Core Binding Factor Alpha 1 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q7277986