Chemicals and Drugs

Cyclizine

A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)

Chemical Identity

Chemical Information

Molecular Formula
C18H22N2
Molecular Weight
266.4 g/mol
CAS Registry No.
82-92-8
IUPAC Name
1-benzhydryl-4-methylpiperazine
InChIKey
UVKZSORBKUEBAZ-UHFFFAOYSA-N
SMILES
CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3
MeSH Unique ID
D003501
Source
PubChem CID 6726

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Cyclizine HCl
  • Cyclizine Hydrochloride
  • Marezine
  • HCl, Cyclizine
  • Hydrochloride, Cyclizine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Cyclizine. Medical Subject Headings (MeSH). 2026. Unique ID D003501. http://id.nlm.nih.gov/mesh/2026/D003501
  2. Cyclizine. In: Wikipedia. https://en.wikipedia.org/wiki/Cyclizine
  3. Cyclizine. In: Wikidata. https://www.wikidata.org/wiki/Q867308
  4. Cyclizine. In: PubChem Compound. CID 6726. https://pubchem.ncbi.nlm.nih.gov/compound/6726