Structured Summary
Abstract
A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
10 entry terms
- 1,4-Cineole 2-exo-Monooxygenase
- CYP2B6
- CYPIIB6
- Cytochrome P450 2B6
- 1,4 Cineole 2 exo Monooxygenase
- 2-exo-Monooxygenase, 1,4-Cineole
- CYP2B6, Cytochrome P-450
- Cytochrome P 450 CYP2B6
- P-450 CYP2B6, Cytochrome
- P450 2B6, Cytochrome
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2015
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Cytochrome P-450 CYP2B6. Medical Subject Headings (MeSH). 2026. Unique ID D065702. http://id.nlm.nih.gov/mesh/2026/D065702
- Cytochrome P-450 CYP2B6. In: Wikidata. https://www.wikidata.org/wiki/Q5014958