Structured Summary
Abstract
A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.
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Classification
Broader headings
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Synonyms
12 entry terms
- CYP2J2
- Cytochrome P 450 CYP2J2
- Arachidonate Epoxygenase
- Arachidonic Acid Epoxygenase
- Cytochrome P-450 Arachidonate Oxygenase
- Cytochrome P-450 Epoxygenase
- NADPH-Dependent Arachidonic Acid Epoxygenase
- Acid Epoxygenase, Arachidonic
- Cytochrome P 450 Arachidonate Oxygenase
- Epoxygenase, Arachidonate
- Epoxygenase, Arachidonic Acid
- NADPH Dependent Arachidonic Acid Epoxygenase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2022 (1985)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Cytochrome P-450 CYP2J2. Medical Subject Headings (MeSH). 2026. Unique ID D000090762. http://id.nlm.nih.gov/mesh/2026/D000090762
- Cytochrome P-450 CYP2J2. In: Wikidata. https://www.wikidata.org/wiki/Q21110752