Chemicals and Drugs

Cytochrome P-450 CYP4A

A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as OCTANES and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A P450 oxidoreductase that catalyzes the hydroxylation of the terminal carbon of linear hydrocarbons such as OCTANES and FATTY ACIDS in the omega position. The enzyme may also play a role in the oxidation of a variety of structurally unrelated compounds such as XENOBIOTICS, and STEROIDS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

38 entry terms
  • Alkane 1-Hydroxylase
  • Alkane 1-Monooxygenase
  • Alkane Hydroxylase
  • CYP4A
  • Cytochrome P-450 4A
  • Cytochrome P-450 IVA
  • Fatty Acid Omega-Hydroxylase
  • Laurate Omega-Hydroxylase
  • Lauric Acid (Omega-1)-Hydroxylase
  • Lauric Acid Hydroxylase
  • Lauric Acid Monooxygenase
  • Lauric Acid Omega-hydroxylase
  • Omega-1 Hydroxylase
  • Omega-Hydroxylase
  • Omega-Lauryl Hydroxylase
  • Acid Hydroxylase, Lauric
  • Acid Omega-Hydroxylase, Fatty
  • Acid Omega-hydroxylase, Lauric
  • Alkane 1 Hydroxylase
  • Alkane 1 Monooxygenase
  • CYP4A, Cytochrome P-450
  • Cytochrome P 450 4A
  • Cytochrome P 450 CYP4A
  • Cytochrome P 450 IVA
  • Fatty Acid Omega Hydroxylase
  • Hydroxylase, Alkane
  • Hydroxylase, Omega-1
  • Hydroxylase, Omega-Lauryl
  • Laurate Omega Hydroxylase
  • Lauric Acid Omega hydroxylase
  • Omega 1 Hydroxylase
  • Omega Hydroxylase
  • Omega Lauryl Hydroxylase
  • Omega-Hydroxylase, Fatty Acid
  • Omega-Hydroxylase, Laurate
  • Omega-hydroxylase, Lauric Acid
  • P-450 4A, Cytochrome
  • P-450 CYP4A, Cytochrome

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS

MeSH Record

History Note

2004(2015)

MeSH Record

Previous Indexing

  • Cytochrome P-450 Enzyme System (1982-2003)
  • Lauric Acids (1979-1981)
  • Mixed Function Oxygenases (1982-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Cytochrome P-450 CYP4A. Medical Subject Headings (MeSH). 2026. Unique ID D042926. http://id.nlm.nih.gov/mesh/2026/D042926
  2. Cytochrome P-450 CYP4A. In: Wikidata. https://www.wikidata.org/wiki/Q76943575