Chemicals and Drugs

DNA-Directed DNA Polymerase

DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.

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Classification

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MeSH Record

Synonyms

13 entry terms
  • DNA Polymerase
  • DNA Polymerases
  • DNA-Dependent DNA Polymerases
  • DNA Dependent DNA Polymerases
  • DNA Directed DNA Polymerase
  • DNA Polymerase, DNA-Directed
  • DNA Polymerases, DNA-Dependent
  • Polymerase, DNA
  • Polymerase, DNA-Directed DNA
  • Polymerases, DNA
  • Polymerases, DNA-Dependent DNA
  • DNA Polymerase N3
  • Polymerase N3, DNA

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

98(68); for DNA POLYMERASE use DNA NUCLEOTIDYLTRANSFERASES 1968-76

MeSH Record

Previous Indexing

  • DNA Nucleotidyltransferases (1968-1976)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QU 141

AMA Style

References

  1. National Library of Medicine. DNA-Directed DNA Polymerase. Medical Subject Headings (MeSH). 2026. Unique ID D004259. http://id.nlm.nih.gov/mesh/2026/D004259
  2. DNA-Directed DNA Polymerase. In: Wikipedia. https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase
  3. DNA-Directed DNA Polymerase. In: Wikidata. https://www.wikidata.org/wiki/Q17141719