Structured Summary
Abstract
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents.
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Classification
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Synonyms
4 entry terms
- DNA Pol II
- DNA Polymerase epsilon
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
84(77); for DNA POLYMERASE EPSILON use DNA POLYMERASE II (NM) 1994-97
MeSH Record
Previous Indexing
- DNA Nucleotidyltransferases (1968-1976)
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AMA Style
References
- National Library of Medicine. DNA Polymerase II. Medical Subject Headings (MeSH). 2026. Unique ID D004257. http://id.nlm.nih.gov/mesh/2026/D004257
- DNA Polymerase II. In: Wikipedia. https://en.wikipedia.org/wiki/DNA_polymerase_II
- DNA Polymerase II. In: Wikidata. https://www.wikidata.org/wiki/Q3502973