Chemicals and Drugs

DNA-Directed RNA Polymerases

Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).

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MeSH Record

Synonyms

17 entry terms
  • DNA-Dependent RNA Polymerases
  • DNA-Directed RNA Polymerase
  • RNA Polymerase
  • RNA Polymerases
  • Transcriptases
  • DNA Dependent RNA Polymerases
  • DNA Directed RNA Polymerase
  • DNA Directed RNA Polymerases
  • Polymerase, DNA-Directed RNA
  • Polymerase, RNA
  • Polymerases, DNA-Dependent RNA
  • Polymerases, DNA-Directed RNA
  • Polymerases, RNA
  • RNA Polymerase, DNA-Directed
  • RNA Polymerases, DNA-Dependent
  • RNA Polymerases, DNA-Directed
  • Transcriptase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2003(1973)

MeSH Record

Previous Indexing

  • RNA Nucleotidyltransferases (1968-1972)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.696w.445w.735.270w

MeSH Record

NLM Classification

QU 141

AMA Style

References

  1. National Library of Medicine. DNA-Directed RNA Polymerases. Medical Subject Headings (MeSH). 2026. Unique ID D012321. http://id.nlm.nih.gov/mesh/2026/D012321
  2. DNA-Directed RNA Polymerases. In: Wikipedia. https://en.wikipedia.org/wiki/RNA_polymerase
  3. DNA-Directed RNA Polymerases. In: Wikidata. https://www.wikidata.org/wiki/Q272631