Chemicals and Drugs

RNA Polymerase II

A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • DNA-Dependent RNA Polymerase II
  • RNA Pol II
  • RNA Polymerase B
  • DNA Dependent RNA Polymerase II

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

84(77); was see under RNA POLYMERASES 1977-83

MeSH Record

Previous Indexing

  • RNA Nucleotidyltransferases (1968-1972)
  • RNA Polymerases (1973-1976)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. RNA Polymerase II. Medical Subject Headings (MeSH). 2026. Unique ID D012319. http://id.nlm.nih.gov/mesh/2026/D012319
  2. RNA Polymerase II. In: Wikipedia. https://en.wikipedia.org/wiki/RNA_polymerase_II
  3. RNA Polymerase II. In: Wikidata. https://www.wikidata.org/wiki/Q15334993