Phenomena and Processes

Death Domain

A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Death Domains

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Amino Acid Sequence (1995-2016)
  • Receptors, Death Domain (2007-2016)
  • Receptors, Tumor Necrosis Factor (1995-2016)

MeSH Hierarchy

Tree Number

  1. G02.111.570.820w.709.275.750w.500.395.500w

AMA Style

References

  1. National Library of Medicine. Death Domain. Medical Subject Headings (MeSH). 2026. Unique ID D000071459. http://id.nlm.nih.gov/mesh/2026/D000071459
  2. Death Domain. In: Wikipedia. https://en.wikipedia.org/wiki/Death_domain
  3. Death Domain. In: Wikidata. https://www.wikidata.org/wiki/Q5247322