Chemicals and Drugs

Decorin

A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Bone Proteoglycan II
  • DSPG-II
  • Proteoglycan II, Bone

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.930w.750w.625
  2. D09w.400w.430w.930w.875.500
  3. D09w.698w.735w.700.750
  4. D12.776w.395w.650w.750w.625
  5. D12.776w.395w.650w.875.500
  6. D12.776w.860w.300.806.750

AMA Style

References

  1. National Library of Medicine. Decorin. Medical Subject Headings (MeSH). 2026. Unique ID D058575. http://id.nlm.nih.gov/mesh/2026/D058575
  2. Decorin. In: Wikidata. https://www.wikidata.org/wiki/Q24785778