Structured Summary
Abstract
A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS.
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Classification
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MeSH Record
Synonyms
12 entry terms
- SLRP Proteoglycan
- SLRP Proteoglycans
- Small Leucine Rich Proteoglycan
- Small Leucine-Rich Proteoglycan
- Small Leucine-Rich Repeat Proteoglycan
- Small Leucine-Rich Repeat Proteoglycans
- Leucine-Rich Proteoglycan, Small
- Proteoglycan, SLRP
- Proteoglycan, Small Leucine-Rich
- Small Leucine Rich Proteoglycans
- Small Leucine Rich Repeat Proteoglycan
- Small Leucine Rich Repeat Proteoglycans
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Proteoglycans (1996-2016)
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Tree Numbers
AMA Style
References
- National Library of Medicine. Small Leucine-Rich Proteoglycans. Medical Subject Headings (MeSH). 2026. Unique ID D000071232. http://id.nlm.nih.gov/mesh/2026/D000071232
- Small Leucine-Rich Proteoglycans. In: Wikidata. https://www.wikidata.org/wiki/Q66589623