Chemicals and Drugs

Lumican

A small leucine-rich proteoglycan that contains 10 tandem leucine repeats and four N-linked sites within the leucine repeat region that may be substituted with KERATAN SULFATE. These properties and its horseshoe shape allow it to mediate interactions among COLLAGEN molecules within fibrils. It is expressed in most mesenchymal tissues as well as the CORNEA, where it functions to maintain transparency.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A small leucine-rich proteoglycan that contains 10 tandem leucine repeats and four N-linked sites within the leucine repeat region that may be substituted with KERATAN SULFATE. These properties and its horseshoe shape allow it to mediate interactions among COLLAGEN molecules within fibrils. It is expressed in most mesenchymal tissues as well as the CORNEA, where it functions to maintain transparency.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Lumican Proteoglycan

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1978)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.930w.875.750
  2. D09w.698w.735w.700.875
  3. D12.776w.395w.650w.875.750
  4. D12.776w.860w.300.806.875

AMA Style

References

  1. National Library of Medicine. Lumican. Medical Subject Headings (MeSH). 2026. Unique ID D000071234. http://id.nlm.nih.gov/mesh/2026/D000071234
  2. Lumican. In: Wikidata. https://www.wikidata.org/wiki/Q24722919