Chemicals and Drugs

Deleted in Azoospermia 1 Protein

An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

4 entry terms
  • DAZ-1 Protein
  • DAZ1 Protein
  • SPGY Protein
  • DAZ 1 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • RNA-Binding Proteins (1995-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.725w.813.375
  2. D12.776w.664w.962w.813.375

AMA Style

References

  1. National Library of Medicine. Deleted in Azoospermia 1 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000075364. http://id.nlm.nih.gov/mesh/2026/D000075364
  2. Deleted in Azoospermia 1 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21112138