Phenomena and Processes

RNA Recognition Motif

An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.

MeSH Record

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Broader headings

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See Also

MeSH Record

Synonyms

5 entry terms
  • RRM Motif
  • Ribonucleoprotein Domain
  • RNA Recognition Motifs
  • RRM Motifs
  • Ribonucleoprotein Domains

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Amino Acid Sequence (1989-2016)
  • RNA-Binding Proteins (1991-2016)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. RNA Recognition Motif. Medical Subject Headings (MeSH). 2026. Unique ID D000071377. http://id.nlm.nih.gov/mesh/2026/D000071377
  2. RNA Recognition Motif. In: Wikipedia. https://en.wikipedia.org/wiki/RNA_recognition_motif
  3. RNA Recognition Motif. In: Wikidata. https://www.wikidata.org/wiki/Q24768845