Structured Summary
Abstract
A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.
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MeSH Record
Synonyms
9 entry terms
- Delta 5 Desaturase
- Delta-5-FADase
- Fatty Acid Delta-5-Desaturase
- 5 Desaturase, Delta
- Acid Delta-5-Desaturase, Fatty
- Delta 5 FADase
- Delta-5-Desaturase, Fatty Acid
- Desaturase, Delta 5
- Fatty Acid Delta 5 Desaturase
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2022 (1981)
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AMA Style
References
- National Library of Medicine. Delta-5 Fatty Acid Desaturase. Medical Subject Headings (MeSH). 2026. Unique ID D000090943. http://id.nlm.nih.gov/mesh/2026/D000090943
- Delta-5 Fatty Acid Desaturase. In: Wikidata. https://www.wikidata.org/wiki/Q21137320