Chemicals and Drugs

Deoxyribonuclease HpaII

One of the Type II site-specific deoxyribonucleases (EC 3.1.21.4). It recognizes and cleaves the sequences C/CGG and GGC/C at the slash. HpaII is from Haemophilus parainfluenzae. Several isoschizomers have been identified. EC 3.1.21.-.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the Type II site-specific deoxyribonucleases (EC 3.1.21.4). It recognizes and cleaves the sequences C/CGG and GGC/C at the slash. HpaII is from Haemophilus parainfluenzae. Several isoschizomers have been identified. EC 3.1.21.-.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • DNA Restriction Enzyme HpaII
  • Endodeoxyribonuclease HpaII
  • Endonuclease HpaII
  • BsuF Endonuclease
  • Deoxyribonuclease MspI
  • MspI Endonuclease
  • SecII Endonuclease

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

96; was ENDODEOXYRIBONUCLEASE HPAII (NM) 1980-95

MeSH Record

Previous Indexing

  • DNA Restriction Enzymes (1980-1988)
  • Deoxyribonucleases, Type II Site-Specific (1989-1995)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Deoxyribonuclease HpaII. Medical Subject Headings (MeSH). 2026. Unique ID D019003. http://id.nlm.nih.gov/mesh/2026/D019003
  2. Deoxyribonuclease HpaII. In: Wikidata. https://www.wikidata.org/wiki/Q76396431