Structured Summary
Abstract
A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
Chemical Identity
Chemical Information
- Molecular Formula
- C23H26N2O2
- Molecular Weight
- 362.5 g/mol
- CAS Registry No.
- 21888-98-2
- IUPAC Name
- (3S)-3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione
- InChIKey
- LQQIVYSCPWCSSD-HSZRJFAPSA-N
- SMILES
- C1CN(CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
- MeSH Unique ID
- D003909
- Source
- PubChem CID 30843
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
10 entry terms
- Dexbenzetimid
- Dexbenzetimide
- dextro-Benzetimide
- dextro Benzetimide
- Benzetimide
- R-16470
- Spasmentral
- Tremblex
- R 16470
- R16470
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an antiparkinson agent
MeSH Record
History Note
91(75); was see under PIPERIDINES 1975-90
MeSH Record
Previous Indexing
- Benzyl Compounds (1972-1974)
- Piperidones (1972-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Dexetimide. Medical Subject Headings (MeSH). 2026. Unique ID D003909. http://id.nlm.nih.gov/mesh/2026/D003909
- Dexetimide. In: Wikipedia. https://en.wikipedia.org/wiki/Dexetimide
- Dexetimide. In: Wikidata. https://www.wikidata.org/wiki/Q904647
- Dexetimide. In: PubChem Compound. CID 30843. https://pubchem.ncbi.nlm.nih.gov/compound/30843