Chemicals and Drugs

Dicyclomine

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.

Chemical Identity

Chemical Information

Molecular Formula
C19H35NO2
Molecular Weight
309.5 g/mol
CAS Registry No.
77-19-0
IUPAC Name
2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate
InChIKey
CURUTKGFNZGFSE-UHFFFAOYSA-N
SMILES
CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2
MeSH Unique ID
D004025
Source
PubChem CID 3042

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • Dicycloverin
  • Bentyl
  • Bentylol
  • Di-Cyclonex
  • Di-Spaz
  • Dibent
  • Diclomin
  • Dicyclomine Hydrochloride
  • Lomine
  • Merbentyl
  • OR-Tyl
  • Spascol
  • Di Cyclonex
  • Di Spaz
  • Hydrochloride, Dicyclomine
  • OR Tyl

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(76); was see under CYCLOHEXANECARBOXYLIC ACIDS 1976-90

MeSH Record

Previous Indexing

  • Cyclohexanecarboxylic Acids (1968-1975)
  • Cyclohexanes (1972-1975)
  • Diethylamines (1974-1975)

MeSH Hierarchy

Tree Numbers

  1. D02w.241w.223.268.300w
  2. D02w.455w.426w.392.368w.367.440w

AMA Style

References

  1. National Library of Medicine. Dicyclomine. Medical Subject Headings (MeSH). 2026. Unique ID D004025. http://id.nlm.nih.gov/mesh/2026/D004025
  2. Dicyclomine. In: Wikipedia. https://en.wikipedia.org/wiki/Dicycloverine
  3. Dicyclomine. In: Wikidata. https://www.wikidata.org/wiki/Q2662662
  4. Dicyclomine. In: PubChem Compound. CID 3042. https://pubchem.ncbi.nlm.nih.gov/compound/3042