Chemicals and Drugs

Dimethyl Fumarate

A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS.

Chemical Identity

Chemical Information

Molecular Formula
C6H8O4
Molecular Weight
144.12 g/mol
CAS Registry No.
624-49-7
IUPAC Name
dimethyl (E)-but-2-enedioate
InChIKey
LDCRTTXIJACKKU-ONEGZZNKSA-N
SMILES
COC(=O)/C=C/C(=O)OC
MeSH Unique ID
D000069462
Source
PubChem CID 637568

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

19 entry terms
  • 2-butenedioic acid, (2E)-, dimethyl ester
  • Dimethylfumarate
  • Fumarate, Dimethyl
  • BG 00012
  • BG 12 compound
  • BG-00012
  • BG-12 compound
  • BG00012
  • BG12 compound
  • FAG 201
  • FAG-201
  • FAG201
  • Fumaderm
  • Tecfidera
  • 00012, BG
  • 12 compound, BG
  • 201, FAG
  • compound, BG 12
  • compound, BG12

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1988)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Dimethyl Fumarate. Medical Subject Headings (MeSH). 2026. Unique ID D000069462. http://id.nlm.nih.gov/mesh/2026/D000069462
  2. Dimethyl Fumarate. In: Wikipedia. https://en.wikipedia.org/wiki/Dimethyl_fumarate
  3. Dimethyl Fumarate. In: Wikidata. https://www.wikidata.org/wiki/Q418123
  4. Dimethyl Fumarate. In: PubChem Compound. CID 637568. https://pubchem.ncbi.nlm.nih.gov/compound/637568